Nuclear factor-erythroid-2-related factor 2 (Nrf2) is a transcription factor that regulates the antioxidant response of the body. It is the primary cellular defense against the cytotoxic effects of oxidative stress. Resvoxitrol is a unique combination of phytonutrients designed to enhance antioxidant potential by stimulating Nrf2, a dynamic pathway known to increase the production of the body’s most important cellular antioxidants. This unique combination of truebroc™, turmeric, andrographis, and resveratrol provides potent free radical scavenging potential, maintaining normal inflammatory balance, and induction of intracellular antioxidant production.

SAMe is a naturally occurring metabolite found in the human body as well as in plant and animal foods. SAMe is the most active of all methyl donors and has been compared to ATP in its importance for the body. It is involved in the synthesis of neurotransmitters, melatonin production, phospholipids, and polyamines, which control cellular growth. SAMe is an amino acid that works in the liver to remove xenoestrogens (harmful environmental estrogens). SAMe also contains the necessary cofactors in order to help the body absorb and use SAMe.

Research on SAMe has proven the following benefits in the brain: depression, cognitive deficit, appetite reduction, improved neurotransmitter synthesis, and receptor binding.

Research on SAMe has also shown possible reduction of TNF-alpha, reduction of fibromyalgia pain and joint damage, and joint regeneration in osteo and rheumatoid arthritis.  Research on SAMe has also shown possible benefits on the liver: protection from toxins, drugs and alcohol use, hepatitis, cirrhosis, fibrosis, and increases liver glutathione levels.

Dosage: Take 1-2 capsules two times per day or as recommended by your healthcare professional.

Contraindications: Consult with your health care practitioner before beginning SAMe if you are being treated for anxiety, bipolar disorder, depression, or if you are taking SSRIs.